Upgrade Acer E1-531 RAM from 1333mhz RAM to 1600mhz?

As E1-531 supports DDR3 1333mhz 1.5v sodimm is it possible to be upgraded with DD3 1600mhz sticks?

I am using 2x2GB DDR3 1333mhz

I want to replace 1x2GB DD3 1333mhz with 1x4GB DD3 1600mhz

So the final result will be 1x4GB DD3 1600mhz + 1x2GB DD3 1333mhz = 6GB RAM with different kind of sticks.

Is it ok, is it compatible and will it works without problems afterwards?

Thanks